![De novo design of a four-fold symmetric TIM-barrel protein with atomic-level accuracy | Nature Chemical Biology De novo design of a four-fold symmetric TIM-barrel protein with atomic-level accuracy | Nature Chemical Biology](https://media.springernature.com/lw685/springer-static/image/art%3A10.1038%2Fnchembio.1966/MediaObjects/41589_2016_Article_BFnchembio1966_Fig3_HTML.jpg)
De novo design of a four-fold symmetric TIM-barrel protein with atomic-level accuracy | Nature Chemical Biology
![The TIM Barrel Architecture Facilitated the Early Evolution of Protein-Mediated Metabolism | SpringerLink The TIM Barrel Architecture Facilitated the Early Evolution of Protein-Mediated Metabolism | SpringerLink](https://media.springernature.com/lw685/springer-static/image/art%3A10.1007%2Fs00239-015-9722-8/MediaObjects/239_2015_9722_Fig1_HTML.gif)
The TIM Barrel Architecture Facilitated the Early Evolution of Protein-Mediated Metabolism | SpringerLink
![De Novo Design of a Highly Stable Ovoid TIM Barrel: Unlocking Pocket Shape towards Functional Design | BioDesign Research De Novo Design of a Highly Stable Ovoid TIM Barrel: Unlocking Pocket Shape towards Functional Design | BioDesign Research](https://spj.science.org/cms/10.34133/2022/9842315/asset/76608f1a-8741-4256-8176-4cf41257df0c/assets/graphic/9842315.fig.001.jpg)
De Novo Design of a Highly Stable Ovoid TIM Barrel: Unlocking Pocket Shape towards Functional Design | BioDesign Research
![Structures from TIM barrel fold c.1 and its variant fold c.6. Panel... | Download Scientific Diagram Structures from TIM barrel fold c.1 and its variant fold c.6. Panel... | Download Scientific Diagram](https://www.researchgate.net/publication/5615421/figure/fig7/AS:213882502160404@1428004970619/Structures-from-TIM-barrel-fold-c1-and-its-variant-fold-c6-Panel-a-d1clxa-a.png)
Structures from TIM barrel fold c.1 and its variant fold c.6. Panel... | Download Scientific Diagram
![A newly introduced salt bridge cluster improves structural and biophysical properties of de novo TIM barrels - Kordes - 2022 - Protein Science - Wiley Online Library A newly introduced salt bridge cluster improves structural and biophysical properties of de novo TIM barrels - Kordes - 2022 - Protein Science - Wiley Online Library](https://onlinelibrary.wiley.com/cms/asset/1dfeeb3b-148b-4592-9045-6a834dbd9cdf/pro4249-fig-0001-m.jpg)
A newly introduced salt bridge cluster improves structural and biophysical properties of de novo TIM barrels - Kordes - 2022 - Protein Science - Wiley Online Library
![Tight and specific lanthanide binding in a de novo TIM barrel with a large internal cavity designed by symmetric domain fusion | PNAS Tight and specific lanthanide binding in a de novo TIM barrel with a large internal cavity designed by symmetric domain fusion | PNAS](https://www.pnas.org/cms/10.1073/pnas.2008535117/asset/498255c2-6414-4601-8ab7-c3a4deda28bf/assets/images/large/pnas.2008535117fig01.jpg)
Tight and specific lanthanide binding in a de novo TIM barrel with a large internal cavity designed by symmetric domain fusion | PNAS
![Cartoon representation of a TIM-barrel protein (PDB entry: 1n55). The... | Download Scientific Diagram Cartoon representation of a TIM-barrel protein (PDB entry: 1n55). The... | Download Scientific Diagram](https://www.researchgate.net/publication/40681258/figure/fig4/AS:196088897249289@1423762644517/Cartoon-representation-of-a-TIM-barrel-protein-PDB-entry-1n55-The-structural-location.png)
Cartoon representation of a TIM-barrel protein (PDB entry: 1n55). The... | Download Scientific Diagram
![Heme-binding enables allosteric modulation in an ancient TIM-barrel glycosidase | Nature Communications Heme-binding enables allosteric modulation in an ancient TIM-barrel glycosidase | Nature Communications](https://media.springernature.com/full/springer-static/image/art%3A10.1038%2Fs41467-020-20630-1/MediaObjects/41467_2020_20630_Fig1_HTML.png)
Heme-binding enables allosteric modulation in an ancient TIM-barrel glycosidase | Nature Communications
![Correlation of fitness landscapes from three orthologous TIM barrels originates from sequence and structure constraints | Nature Communications Correlation of fitness landscapes from three orthologous TIM barrels originates from sequence and structure constraints | Nature Communications](https://media.springernature.com/full/springer-static/image/art%3A10.1038%2Fncomms14614/MediaObjects/41467_2017_Article_BFncomms14614_Fig1_HTML.jpg)
Correlation of fitness landscapes from three orthologous TIM barrels originates from sequence and structure constraints | Nature Communications
![Similarity in shape dictates signature intrinsic dynamics despite no functional conservation in TIM Barrel enzymes | Reuter group | UiB Similarity in shape dictates signature intrinsic dynamics despite no functional conservation in TIM Barrel enzymes | Reuter group | UiB](https://www.uib.no/sites/w3.uib.no/files/styles/content_main/public/media/journal.pcbi_.1004834.g001.png?itok=NCDMLPh0×tamp=1579194092)